Cefepime USP

 Presentation

• Ximepime 500 mg IM/IV injection: Each vial contains Cefepime 500 mg as Cefepime Hydrochloride USP with L-Arginine sterile powder.
• Ximepime 1 gm IM/IV injection: Each vial contains Cefepime 1 gm as Cefepime Hydrochloride USP with L-Arginine sterile powder.
• Ximepime 2 gm IM/IV injection: Each vial contains Cefepime 2 gm as Cefepime Hydrochloride USP with L-Arginine sterile powder.

Description

Ximepime injection is a fourth generation broad spectrum cephalosporin antibiotic which inhibits bacterial cell wall synthesis by binding to one or more of the penicillin binding proteins (PBPs). It is highly resistant to hydrolysis by most beta-lactamases and exhibits rapid penetration into gram-negative bacterial cells. Its broad spectrum of activity encompasses a wide range of bacteria, including gram-negative microorganisms, such as Enterobacter, Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis and Pseudomonas aeruginosa, and gram-positive microorganism, such as methicillin-susceptible Staphylococcus aureus, Streptococcus pneumoniae, Streptococcus pyogenes, and Viridans group streptococci. It is indicated for Pneumonia (moderate to severe), Uncomplicated and Complicated Urinary Tract Infections (including pyelonephritis), Uncomplicated Skin and Skin Structure Infections, Complicated Intra-abdominal Infections, Empiric Therapy for Febrile Neutropenic Patients.

Therapeutic Class

Antibiotic, 4th generation cephalosporin (Beta-lactam)

 

Prescribing Information