Fibrostat
Presentation
Fibrostat 500 Injection: Each ampoule contains Tranexamic Acid BP 500 mg.
Fibrostat 500 Cap.: Each capsule contains Tranexamic Acid BP 500 mg.
Description
Tranexamic acid is an antifibrinolytic compound that competitively inhibits the activation of plasminogen to plasmin. It is a synthetic lysine amino acid derivative, which diminishes the dissolution of hemostatic fibrin by plasmin. In the presence of tranexamic acid, the lysine receptor binding sites of plasmin for fibrin are occupied, preventing binding to fibrin monomers, thus preserving and stabilizing fibrin’s matrix structure. Its actions similar to aminocaproic acid but binds more strongly than aminocaproic acid to both the strong and weak receptor sites of the plasminogen molecule. So it is about 10 times more potent in vitro than aminocaproic acid.
Therapeutic Class: Antifibrinolytic
