Omeprazole

Presentation:

OP-20 Capsule: Each capsule contains Omeprazole 20 mg BP As enteric-coated pellets.

OP-40 Capsule: Each capsule contains Omeprazole 40 mg BP As enteric-coated pellets.

OP-40 IV Injection: Each vial contains sterile powder of Omeprazole Sodium BP equivalent to Omeprazole 40 mg.

Description

Omeprazole, a substituted benzimidazole is an inhibitor of gastric acid secretion. It inhibits gastric acid secretion by blocking hydrogen-potassium-adenosine triphosphatase (H+/K+ ATPase) enzyme system in the gastric parietal cell. After oral administration, the onset of the antisecretory effect occurs within one hour, with the maximum effect occurring within two hours, and inhibition of secretion lasts up to 72 hours. When the drug is discontinued, secretory activity returns gradually, over 3 to 5 days. OP is indicated for symptomatic improvement and healing of Peptic acid diseases, which require a reduction in acid secretion.

Therapeutic Class: Anti-ulcerant.

 

Prescribing Information